At IMB, we explore the molecular biology of the nucleus with an overarching focus on gene regulation, epigenetics & genome stability
Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.
- About us
Who we are, where we are & what we do...
- Research
Our scientists & what they are working on...
- Core Facilities
State-of-the-art technologies & services...
- Students & Postdocs
Training programmes we offer junior researchers...
- Seminars & Events
Conferences, meetings, workshops & more...
- Careers
Current opportunities at IMB...
Recent Publications
- Sep 2025 | Cell Rep | LuckUnveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17-…
- Aug 2025 | Cell | StelzlA split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into…
- Aug 2025 | in: Science for a Better Tomorrow (ed. Betz UAK), Springer, Cham, Switzerland | Lemke | Dormann | Wittmann | Ulrich | ...Polymers: The hidden heroes of life.
- Aug 2025 | Nat Commun | Dormann | LemkeCurrent practices in the study of biomolecular condensates: a community comment.
- Aug 2025 | Biophys J | Stelzl | KettingMulti-scale simulations of MUT-16 scaffold protein phase separation and client recognition.
- Aug 2025 | EMBO Rep | BarauDNA methylation at retrotransposons protects the germline by preventing NRF1-mediated activation.
- Aug 2025 | eGastroenterology | Vieira-SilvaGut dysbiosis is linked to severe steatosis and enhances its diagnostic performance in MASLD.
- Jul 2025 | Front Mol Biosci | KönigAvaII senses m6A and inosine sites and enables targeted nanopore direct RNA-sequencing.
- Jul 2025 | PLoS One | TüscherSocioeconomic disparities in cognitive impairment, quality of life, and mortality among older adults…
- Jul 2025 | Elife | KettingMeioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells.
Joint Research Initiatives
A centre for basic & clinical research on ageing & age-related disease
A joint initiative on the mechanisms underlying robustness & longevity
A joint PhD programme to discover new ways to understand & treat age-related diseases
A joint PhD programme to understand why diseases are more common in old age and how we can age healthily
The largest network on DNA repair & genome stability in Germany
An initiative bridging the polymer & life sciences to understand biological processes such as ageing
IMB’s flagship PhD training programme on epigenetics, genome stability & ageing
A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience
A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan