The Institute of Molecular Biology (IMB)

Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.

About us
Who we are, where we are & what we do...
Research
Our scientists & what they are working on...
Core Facilities
State-of-the-art technologies & services...
Students & Postdocs
Training programmes we offer junior researchers...
Seminars & Events
Conferences, meetings, workshops & more...
Careers
Current opportunities at IMB...

The funds will be used to establish a new doctoral training programme called CoAGE (“Cohorts for Healthy Ageing”)

The conference will be on "The Evil within: Regulation & Repair of Endogenous DNA Damage"

Congratulations to Claudia!

16 Jul 2025
Seminar | 4R-RTG
The SMC5/6 complex: Jumping through R-loops and other chromatin acrobatics
Prof. Damien D’Amours (University of Ottawa, Canada)
18 Sep 2025
Course
Building a strategic approach to research funding
Dr Gunnar Seemann
18 Sep 2025
Seminar | SFB 1361 Seminar
SFB 1361 Seminar with Dr Rushad Pavri

Access the full IMB events calendar by clicking here

Recent Publications

Jun 2025 | Nucleic Acids Res | Butter F | Ketting RF
ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2…
Jun 2025 | ChemMedChem | Stelzl
Proton first: rationalizing a proton transfer in a protein-fragment complex.
Jun 2025 | Genes Dev | Keller Valsecchi
Sex-specific transcriptome dynamics of Anopheles gambiae during embryonic development.
Jun 2025 | Cell Chem Biol | Dormann D
Two sides of a co(i)ndensate.
Jun 2025 | Genes Dev | Beli P
The USP11/TCEAL1 complex promotes transcription elongation to sustain oncogenic gene expression in…
May 2025 | DNA Repair | Ulrich
Reversible association of ubiquitin with PCNA is important for template switching in S. cerevisiae.
May 2025 | eGastroenterology | Vieira-Silva S
Dietary convergence induces individual responses in faecal microbiome composition.
May 2025 | EMBO Rep | Luke
RNase H1 and Sen1 ensure that transient TERRA R-loops promote the repair of short telomeres.
May 2025 | Nat Commun | Stelzl | Dormann
Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates.
May 2025 | Nat Commun | Dormann
Structural basis of phosphorylation-independent nuclear import of CIRBP by TNPO3.

A centre for basic & clinical research on ageing & age-related disease
with Mainz University & its Medical Center, the Leibniz Institute for Resilience Research & TRON
A joint initiative on the mechanisms underlying robustness & longevity
with groups at Mainz University
A joint PhD programme to discover new ways to understand & treat age-related diseases
with Mainz University & its Medical Center
The largest network on DNA repair & genome stability in Germany
with groups in Mainz, Darmstadt, Frankfurt & Munich
An initiative bridging the polymer & life sciences to understand biological processes such as ageing
with Mainz University, its Medical Center & the Max Planck Institute for Polymer Research
IMB’s flagship PhD training programme on epigenetics, genome stability & ageing
with Mainz University & its Medical Center
A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience
with groups from Mainz University & its Medical Center
A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan
with Mainz University’s Faculty of Biology
IMB's summer school on epigenetics & genome stability in health, ageing & disease, for Master & undergraduate students
with Mainz University's Faculty of Biology

News

IMB and the Centre for Healthy Ageing (CHA) receive €1.3 million to study the causes of age-related diseases

Save the date for the IMB/SFB 1361 Conference in March 2026!

Claudia Keller Valsecchi recieves the Friedrich Miescher Award 2025

Upcoming Events

16 Jul 2025

18 Sep 2025

18 Sep 2025

Joint Research Initiatives

A centre for basic & clinical research on ageing & age-related disease

A joint initiative on the mechanisms underlying robustness & longevity

A joint PhD programme to discover new ways to understand & treat age-related diseases

The largest network on DNA repair & genome stability in Germany

An initiative bridging the polymer & life sciences to understand biological processes such as ageing

IMB’s flagship PhD training programme on epigenetics, genome stability & ageing

A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience

A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan

IMB's summer school on epigenetics & genome stability in health, ageing & disease, for Master & undergraduate students