Bioinformatics is a powerful tool that allows us to simultaneously analyse large numbers of genes, proteins, or cells. Using computational biology approaches including artificial intelligence, we can decode molecular mechanisms of gene regulation, chromatin organisation, and DNA repair, or screen for mutations in patients on a genome-wide scale. Our scientists use computational biology to identify changes in gene regulation between diseased and normal cells to make predictions about the mechanisms underlying disease.
Key techniques used: Bioinformatics analysis, neural networks, deep learning, mathematical modelling, next-generation sequencing (DNA and RNA-seq), mass spectrometry, high-throughput microscopy, random mutagenesis screening.
Keywords: Artificial intelligence, machine learning, programming, computer vision, modelling.