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At IMB, we explore the molecular biology of the nucleus with an overarching focus on gene regulation, epigenetics & genome stability

University Medical Center (UMC) Mainz

Maria Felicia Basilicata  Christian Behl  Benedikt Berninger  Luciana Berod  Tobias Bopp  Andreas Daiber  Sven Danckwardt  Carsten Deppermann  Stephan Grabbe  Thomas Hofmann  Thomas Kindler  Daniela Kramer  Daniela Krause  Dilja Krueger-Burg  Michael Kühn  Beat Lutz  Johannes Mayer  Wolfram Ruf  Susann Schweiger  Natalia Soshnikova  Tim Sparwasser  Oliver Tüscher  Sara Vieira-Silva  Ari Waisman  Philipp Wild  Jennifer Winter  Fatemeh Zare-Shahneh 

RNA-mediated regulation of gene expression

Jennifer Winter

Research website

Positions held

  • Since 2013: Head of Molecular Cytogenetic Diagnostics, Institute of Human Genetics, University Medical Center (UMC), Mainz
  • Since 2012: Group leader, Institute of Human Genetics, University Medical Center (UMC), Mainz
  • 2008 - 2012: Project group leader, department of Molecular Embryology, MPI of Immunobiology and Epigenetics, Freiburg

Education

  • Since 2013: Further education as Fachhumangenetikerin
  • Since 2012: Preparation of habilitation
  • 2003 - 2008: Postdoctoral research with Dr. S. Schweiger, MPI for Molecular Genetics, Berlin
  • 2000 - 2003: PhD with Dr. S. Schweiger, Max Planck Institute (MPI) for Molecular Genetics, Berlin
  • 2000: Diploma thesis at the German Rheumatism Research Centre Berlin; Diploma in Biology, University Bielefeld

Selected publications by Jennifer Winter

Casanovas S, Schlichtholz L, Mühlbauer S, Dewi S, Schüle M, Strand D, Strand S, Zografidou L, Winter J (2020) Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters. Front Mol Neurosci, 13:66 Link

Kahrizi K, Huber M, Galetzka D, Dewi S, Schröder J, Weis E, Kariminejad A, Fattahi Z, Ropers HH, Schweiger S, Najmabadi H, Winter J (2019) Homozygous variants in the gene SCAPER cause syndromic intellectual disability. Am J Med Genet A, 179(7):1214-1225 Link

Wenzel M, Schüle M, Casanovas S, Strand D, Strand S, Winter J (2016) Identification of a classic nuclear localization signal at the N terminus that regulates the subcellular localization of Rbfox2 isoforms during differentiation of NMuMG and P19 cells. FEBS Lett, 590(24):4453-4460 Link

Rago L, Beattie R, Taylor V, Winter J (2014) miR379-410 cluster miRNAs regulate neurogenesis and neuronal migration by fine-tuning N-cadherin. EMBO J, 33(8):906-20 Link

Braeutigam C, Rago L, Rolke A, Waldmeier L, Christofori G, Winter J (2014) The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Oncogene, 33(9):1082-92 Link